151 research outputs found

    Dataset on electrical single-family house and heat pump load profiles in Germany

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    This paper describes a dataset of residential electricity household and heat pump load profiles, measured in 38 single-family houses in Northern Germany. We provide data per household of apparent, active and reactive power (W), voltage (V), current (A) and the power factor (no unit) in 10 seconds to 60 minutes temporal resolution from May 2018 to the end of 2020. We validated the dataset both in itself, comparing different measurements that should produce the same results, and externally to standard load profiles and found no major inconsistencies. We identified an average consumption per single-family house with 2.38 inhabitants of 2829 kWh for the household and an additional 4993 kWh for the heat pump. The dataset can support the understanding of patterns in electrical load curves and can help to estimate the additional load on distribution networks induced by heat pumps

    Reduced complexity of activity patterns in patients with Chronic Fatigue Syndrome: a case control study

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    ABSTRACT: BACKGROUND: Chronic fatigue syndrome (CFS) is an illness characterised by pervasive physical and mental fatigue without specific identified pathological changes. Many patients with CFS show reduced physical activity which, though quantifiable, has yielded little information to date. Nonlinear dynamic analysis of physiological data can be used to measure complexity in terms of dissimilarity within timescales and similarity across timescales. A reduction in these objective measures has been associated with disease and ageing. We aimed to test the hypothesis that activity patterns of patients with CFS would show reduced complexity compared to healthy controls. METHODS: We analysed continuous activity data over 12 days from 42 patients with CFS and 21 matched healthy controls. We estimated complexity in two ways, measuring dissimilarity within timescales by calculating entropy after a symbolic dynamic transformation of the data and similarity across timescales by calculating the fractal dimension using allometric aggregation. RESULTS: CFS cases showed reduced complexity compared to controls, as evidenced by reduced dissimilarity within timescales (mean (SD) Renyi(3) entropy 4.05 (0.21) vs. 4.30 (0.09), t = -6.6, p < 0.001) and reduced similarity across timescales (fractal dimension 1.19 (0.04) vs. 1.14 (0.04), t = 4.2, p < 0.001). This reduction in complexity persisted after adjustment for total activity. CONCLUSION: Patients with CFS show evidence of reduced complexity of activity patterns. Measures of complexity applied to activity have potential value as objective indicators for CFS

    Minimally invasive pancreatic surgery—will robotic surgery be the future?

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    Due to the complexity of the procedures and the texture of the organ itself, pancreatic surgery remains a challenge in the field of visceral surgery. During the past decade, a minimally invasive approach to pancreatic surgery has gained distribution in clinical routine, extending from left-sided procedures to pancreatic head resections. While a laparoscopic approach has proven beneficial for many patients with left-sided pancreatic pathologies, the complex reconstruction in pancreas head resections remains worrisome with the laparoscopic approach. The robotic technique was established to overcome such technical constraints while preserving the advantages of the laparoscopic approach. Even though robotic systems are still in development, especially in pancreatoduodenectomy, the current literature demonstrates the feasibility of this approach and stable clinical and oncological outcomes compared to the open technique, albeit only under the condition of such operations being performed by specialist teams in a high-volume setting (>20 robotic pancreaticoduodenectomies per year). The aim of this review is to analyze the current evidence regarding a minimally invasive approach to pancreatic surgery and to review the potential of a robotic approach. Presently, there is still a scarcity of sound evidence and long-term oncological data regarding the role of minimally invasive and robotic pancreatic surgery in the literature, especially in the setting of pancreaticoduodenectomy

    Maritime Studies 2016

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    Das Jahrbuch enthält ausgezeichnete Bachelor- oder Masterarbeiten sowie Forschungsbeitäge und Ergebnissse. In dieser Ausgabe sind folgende Aufsätze enthalten: Vibration analysis based on acoustic and mechanical measurement methods. Ultraschall zur In-situ-Reinigung von Membranen in Membranbioreaktoren (MBR) an Bord von Schiffen - Untersuchung zu den Auswirkungen auf Aktivität und Struktur des Belebtschlammes. Untersuchung der heutigen SOLAS-Regeln bzgl. der Stabilität und Lecksicherheit am Beispiel der Titanic mit Hilfe von Paramarine

    Safety of transanal ileal pouch-anal anastomosis for ulcerative colitis: a retrospective observational cohort study

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    Background: Colectomy with transanal ileal pouch-anal anastomosis (taIPAA) is a surgical technique that can be used to treat benign colorectal disease. Ulcerative colitis is the most frequent inflammatory bowel disease (IBD) and although pharmacological therapy has improved, colectomy rates reach up to 15%. The objective of this study was to determine anastomotic leakage rates and treatment after taIPAA as well as short- and long-term pouch function. Methods: We conducted a retrospective analysis of a prospective database of all patients undergoing taIPAA at an academic tertiary referral center in Germany, between 01/03/2015 and 31/08/2019. Patients with indications other than ulcerative colitis or with adjuvant chemotherapy following colectomy for colorectal carcinoma were excluded for short- and long-term follow up due to diverging postoperative care yet considered for evaluation of anastomotic leakage. Results: A total of 22 patients undergoing taIPAA during the study time-window were included in analysis. Median age at the time of surgery was 32 +/- 12.5 (14-54) years. Two patients developed an anastomotic leakage at 11 days (early anastomotic leakage) and 9 months (late anastomotic leakage) after surgery, respectively. In both patients, pouches could be preserved with a multimodal approach. Twenty patients out of 22 met the inclusion criteria for short and long term follow-up. Data on short-term pouch function could be obtained in 14 patients and showed satisfactory pouch function with only four patients reporting intermittent incontinence at a median stool frequency of 9-10 times per day. In the long-term we observed an inflammation or "pouchitis" in 11 patients and a pouch failure in one patient. Conclusion: Postoperative complication rates in patients with benign colorectal disease remain an area of concern for surgical patient safety. In this pilot study on 22 selected patients, taIPAA was associated with two patients developing anastomotic leakage. Future large-scale validation studies are required to determine the safety and feasibility of taIPAA in patients with ulcerative colitis

    Wind-Solar-Wärmepumpenquartiere: Praxiserfahrungen und Planungshilfen für den erneuerbaren Betrieb von Wärmepumpenquartieren mit minimiertem Primärenergiebedarf

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    Wärmepumpen (WP) bieten großes Potenzial zur Reduzierung des Primärenergiebedarfs und der CO2-Emissionen im Wärmesektor. Besonders hoch fallen diese Reduzierungen aus, wenn der Strom für die Wärmepumpen aus erneuerbaren Energiequellen wie Windenergie oder Photovoltaikanlagen stammt. Bei der Planung und Umsetzung der Wärmeversorgung von einzelnen Gebäuden und ganzen Quartieren mittels Wärmepumpe ergeben sich auf verschiedenen Ebenen allgemeine und technische Fragestellungen. Diese Fragestellungen wurden im Rahmen des Forschungsprojekts Wind-Solar-Wärmepumpenquartier an Hand von Messungen in realen Wärmepumpen-Quartieren und mittels Simulationsstudien untersucht. Die Ergebnisse sind in diesem Bericht zusammengefasst und sollen Hilfestellungen sowie Anregungen zur Planung und Umsetzung von regenerativ betriebenen Wärmepumpenquartieren geben. Dabei gliedert sich der Bericht in die drei folgenden Themenbereiche: Lernen aus der Praxis: Im Rahmen des Projekts wurden zwei Wärmepumpenquartiere untersucht, die sich im Wesentlichen in der Art der Wärmequelle und in ihrem Baujahr unterscheiden. Die bis zu 20-jährigen Betriebserfahrungen und Messdaten aus den Wärmepumpenquartieren liefern umfangreiche Erkenntnisse. Diese lassen eine Bewertung zu, ob innovative Konzepte auch langfristig effizient betrieben werden können und wo noch Handlungsbedarf besteht. Wie können Wärmepumpenquartiere mit erneuerbaren Energien versorgt und Primärenergie (PE) eingespart werden? Bei der Planung von Wärmepumpenquartieren ergeben sich viele Fragestellungen: Welche Wärmequelle ist die beste für die Wärmeversorgung im Quartier? Wie kann der Strombedarf der Wärmepumpen aus erneuerbaren Energieanlagen wie Windenergie und Photovoltaik gedeckt werden? Was sind die relevanten Parameter für eine optimale Auslegung der Windenergie- und Photovoltaik-Anlagen? Welchen Beitrag können Betriebsstrategien und thermische oder elektrische Speicher für einen erneuerbaren Betrieb leisten? Auf Basis von Simulationsstudien werden diese Fragestellungen hinsichtlich der Primärenergieeinsparung untersucht und anhand ihrer Wirksamkeit bewertet. Welche Anforderungen stellen erneuerbar betriebene Wärmepumpenquartiere an die elektrischen Verteilnetze? Wie wirkt sich der Wärmepumpenbetrieb auf die Netzauslastung aus? Welchen Einfluss haben Photovoltaikanlagen auf den Netzbetrieb? Welche weiteren Belastungsfaktoren lassen sich identifizieren? An Hand von verschiedenen Belastungsszenarien wird aufgezeigt, welche Verbraucher und Erzeuger wichtig für die Auslegung der Netze sind und welchen Einfluss die Wahl der Wärmequelle und der Betriebsstrategien der Wärmepumpen auf die Auslastung des Netzes haben

    A cross-sectional study on fatigue, anxiety, and symptoms of depression and their relation with medical status in adult patients with Marfan syndrome:Psychological consequences in Marfan syndrome

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    Marfan syndrome (MFS) is a connective tissue disorder affecting the cardiovascular, ocular, and skeletal system, which may be accompanied by psychological features. This study aimed to determine the prevalence of fatigue, anxiety, and symptoms of depression in MFS patients, and to assess the degree to which sociodemographic and clinical variables are associated with fatigue and psychological aspects. The prevalence of fatigue, anxiety, and symptoms of depression were assessed in two cohorts of MFS patients and compared with healthy controls. The checklist individual strength (CIS), and hospital anxiety and depression scale (HADS) questionnaires were utilized. Medical status was assessed (family history of MFS, aortic root dilatation >40 mm, previous aortic surgery, aortic dissection, chronic pain, skeletal involvement, and scoliosis). Severe fatigue was experienced by 37% of the total MFS cohort (n = 155). MFS patients scored significantly higher on the CIS questionnaire, concerning severe fatigue, as compared with the general Dutch population (p < 0.0001). There were no differences in HADS anxiety or depression scores. In older MFS patients, with a more severe cardiovascular phenotype, chronic pain, and a higher unemployment rate, significantly more symptoms of depression were observed, when compared with the general population (p = 0.027) or compared with younger MFS patients (p = 0.026). Multivariate analysis, showed that anxiety was associated with chronic pain (p = 0.022) and symptoms of depression with unemployment (p = 0.024). MFS patients report significantly more severe fatigue as compared with the general population. Since the cause of fatigue is unclear, more research may be needed. Psychological intervention, for example, cognitive behavioral therapy, may contribute to a reduction in psychological symptoms

    Search for Fractional Charges Produced in Heavy-Ion Collisions at 1.9 GeV/nucleon

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    An experiment was performed to capture fractionally charged particles produced in heavy-ion collisions and to concentrate them in samples suitable for analysis by various techniques. Two of the samples so produced have been searched, with use of an automated version of Millikan\u27s oil-drop apparatus. The beam was 56Fe at 1.9 GeV/nucleon, incident on a lead target. Less than one fractional charge per 1.0× 104 Fe-Pb collisions was found to be produced, and, with further assumptions, less than one per 2.0× 106 collisions
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